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It will direct you to useful resources provided by CCACE researchers and external bodies.There is a ‘wiki’ section for you, and others who have been through the process, to add useful hints and tips, and up-to-date resources particularly relevant to researchers and students in CCACE.Due to limited editorial capacity, a limited number of interim updates for Version 5.2 have been produced. The Handbook editorial team will now proceed to the full production of Version 6 of the Handbook, to be released in 2018.The new chapters are 1, 8, 9, 10, 11, 12, and 21 and are available as pdf versions for Cochrane members. Senior Scientific Editors Julian Higgins and James Thomas have reorganized some material to include recent developments.in children and, when appropriate, to meta-analyse the relation between previous antibiotics prescribed in primary care and resistance.Design and data analysis Systematic review and meta-analysis.

These guidelines provide recommendations that outline the critical aspects of infection prevention and control.Systematic reviews, just like other research articles, can be of varying quality.They are a significant piece of work (the Centre for Reviews and Dissemination at York estimates that a team will take 9-24 months), and to be useful to other researchers and practitioners they should have: It is essential that each review is approached rigorously and with careful attention to detail. The consensus reporting guidelines for different study designs proposed by EQUATOR ( are a useful starting point. If you are proposing to perform a systematic review these provide invaluable detailed advice, and useful examples.Results 58 observational studies investigated 77 783 isolates in urine.In studies from OECD countries, the pooled prevalence of resistance was 53.4% (95% confidence interval 46.0% to 60.8%) for ampicillin, 23.6% (13.9% to 32.3%) for trimethoprim, 8.2% (7.9% to 9.6%) for co-amoxiclav, and 2.1% (0.8 to 4.4%) for ciprofloxacin; nitrofurantoin was the lowest at 1.3% (0.8% to 1.7%).Electronic searches with Me SH terms and text words identified 3115 papers.


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